Fibrous Networks in Biology

Fibrous-Networks-in-Biology_5.8.19-01May 8, 2018
1:00pm – 6:00pm
LRSM Reading Room

Presented by: Penn/Leipzig/Syracuse at the LRSM
Hosts: Paul A. Janmey & Vivek B. Shenoy

Josef Käs, Leipzig
Cell Unjamming, why do rigid tumors contain soft cells?

Alison Patteson, Syracuse
Loss of vimentin enhances 3D cell motility and increases rates of nuclear damage.

Jennifer Schwarz, Syracuse
Loops versus lines and the compression mechanics of semiflexible polymer networks and cells.

Plus: short talks and posters by lab members

 

lunch & discussionlunch & discussionJennifer Schwarz (Syracuse)Mahesh Gandikota (Syracuse)Ehsan Ban (Penn)group discussionEkaterina Grishchuk (Penn)Josef Käs (Leipzig)

 

Schedule

1:00-1:45 Lunch, Discussion
1:45-2:15 Jennifer Schwarz (Syracuse)
Loops versus lines and the compression mechanics of semiflexible polymer networks and cells
2:15-2:30 Xingyu Chen (Penn)
Emergence of tissue-like mechanics from fibrous networks confined by close-packed cells
2:30-2:45 Mahesh Gandikota (Syracuse)
Hierarchical `buckling without bending’ and cerebellar shape
2:45-3:00 Steffen Grosser (Leipzig)
Cell Jamming in Tumors
3:00-3:30 Andrea Liu (Penn)
Exploiting the malleability of disorder to tune properties of mechanical networks
3:30-3:45 Ehsan Ban (Penn)
Triaxial coupling, anomalous Poisson effect, and plasticity of collagen networks
3:45-4:00 Break
4:00-4:15 Frank Sauer (Leipzig)
Tumor traction forces and cell migration in collagen networks
4:15-4:45 Ekaterina Grishchuk (Penn)
Engineering a mechanochemical trigger based on collagen hydrogel and bistable kinase-phosphatase system
4:45-5:15 Alison Patteson (Syracuse)
Loss of vimentin enhances 3D cell motility and increases rates of nuclear damage
5:15-5:30 Carlotta Ficorella (Leipzig)
Cytoskeletal dynamics during cancer cell migration in confined geometries
5:30-6:00 Josef Käs (Leipzig)
Cell Unjamming, why do rigid tumors contain soft cells?