(A) Spatial distribution of particles with different machine-learned softness, strongly correlated with localized particle rearrangements within the glass. (B,C) Rearrangement barriers (entropic and energetic), rescaled to be dimensionless, against the ML-informed excess entropy of thermal configurations. Approximate collapse is observed in the data at the same temperatures relative to the onset of glassy dynamics. Agreement improves as one moves deeper into the supercooled regime.